Тип публикации: статья из журнала

Год издания: 2022

Идентификатор DOI: 10.1097/01.HS9.0000847092.01448.ed

Аннотация: JAK2 exon 12 mutations are seen in about 2-5% of JAK2V617F-negative cases of polycythemia vera (PV). Nowadays about 40 different JAK2 exon 12 mutations associated with PV have been identified and classified. To identify all possible variants, it is necessary to use sequencing. However, due to the high cost of sequencing, developingПоказать полностьюa two- stage algorithm for detect mutations in JAK2 exon 12 using inexpensive screening is of immediate practically necessity. We have previously proposed a two-stage algorithm for detect mutations in JAK2 exon 12 using inexpensive screening test by heteroduplex analysis (Subbotina T et al, Haematologica 2017).

Журнал: HemaSphere

Выпуск журнала: Т. 6, № S3

Номера страниц: 946-947

ISSN журнала: 25729241

• Kurochkin D.V. (Siberian Federal University)
• Maslyukova I.E. (Siberian Federal University)
• Subbotina T.N. (Siberian Federal University)
• Khazieva А.
• Dunaeva E.A. (Central Research Institute of Epidemiology of The Federal Service on Customers' Rights Protection and Human Well-being Surveillance)
• Mironov K.O. (Central Research Institute of Epidemiology of The Federal Service on Customers' Rights Protection and Human Well-being Surveillance)

• Ядро РИНЦ (eLIBRARY.RU)