Cultivation of multipotent mesenchymal bone marrow cells on matrixes made of resorbable bioplastotan

Описание

Тип публикации: статья из журнала

Год издания: 2013

Ключевые слова: Alkaline phosphatase, Differentiation, Extracellular calcium precipitates, Multipotent mesenchymal stromal cells, Osteopontin, Resorbable bioplastotan

Аннотация: Series of cell carriers made of resorbable polyester Bioplastotan, which is a copolymer of 3- And 4-hydroxybutyric acid, are characterized in this work. With use of various technologies membranes, 3D scaffolds, and nanomatrixes formed by ultrafine fibers produced with electrostatic spinning were constructed. All types of scaffolds Показать полностьюprovide adhesion of multipotent mesenchymal stromal cells and are suitable for the cultivation and differentiation of cells in the osteoblastes, that confirmed by detection of extracellular calcium precipitates, alkaline phosphatase activity and osteopontin production in cell culture. © Human stem cells institute, 2013.

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Издание

Журнал: Cellular Transplantation and Tissue Engineering

Выпуск журнала: Vol. 8, Is. 1

Номера страниц: 57-65

Персоны

  • Shishatskaya E.I. (Siberian Branch, Institute of Biophisycs, RAS, Krasnoyarsk, Russian Federation, Siberian Federal University, Krasnoyarsk, Russian Federation)
  • Nikolaeva E.D. (Siberian Branch, Institute of Biophisycs, RAS, Krasnoyarsk, Russian Federation)
  • Shumilova A.A. (Siberian Federal University, Krasnoyarsk, Russian Federation)
  • Shabanov A.V. (Siberian Branch, L.V. Kirensky Institute of Physics, RAS, Krasnoyarsk, Russian Federation)
  • Volova T.G. (Siberian Branch, Institute of Biophisycs, RAS, Krasnoyarsk, Russian Federation, Siberian Federal University, Krasnoyarsk, Russian Federation)

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