Antitumor effect of arabinogalactan and platinum complex

Описание

Тип публикации: статья из журнала

Год издания: 2016

Идентификатор DOI: 10.1134/S1607672916020046

Аннотация: The article presents the results of investigation of antitumor properties of platinum-arabinogalactan complex. We showed the ability of the complex to inhibit the growth of Ehrlich ascites tumor cells. It is found that the distribution of the platinum-arabinogalactan complex is not specific only for tumor cells in mice. The complexПоказать полностьюwas found in all tissues and organs examined (ascites cells, embryonic cells, kidney, and liver). The mechanism of action of the arabinogalactan-platinum complex may be similar to cisplatin as the complex is able to accumulate in tumor cells.

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Издание

Журнал: DOKLADY BIOCHEMISTRY AND BIOPHYSICS

Выпуск журнала: Vol. 467, Is. 1

Номера страниц: 92-94

ISSN журнала: 16076729

Место издания: NEW YORK

Издатель: MAIK NAUKA/INTERPERIODICA/SPRINGER

Авторы

  • Starkov A.K. (Institute of Chemistry and Chemical Technology,Siberian Branch,Russian Academy of Sciences)
  • Kuznetsova S.A. (Siberian Federal University)
  • Zamay T.N. (Kirenskii Institute of Physics,Siberian Branch,Russian Academy of Sciences,Akademgorodok)
  • Savchenko A.A. (Siberian Federal University)
  • Ingevatkin E.V. (Voino-Yasenetskii State Medical University,Ministry of Health of the Russian Federation)
  • Kolovskaya O.S. (Kirenskii Institute of Physics,Siberian Branch,Russian Academy of Sciences,Akademgorodok)
  • Titova N.M. (Siberian Federal University)
  • Luzan N.A. (Siberian Federal University)
  • Silkin P.P. (Siberian Federal University)

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