Тип публикации: статья из журнала

Год издания: 2015

Идентификатор DOI: 10.1126/science.aab3884

Ключевые слова: genomics, historical geography, historical time (human history), Pleistocene, population structure, social history, American Indian, ancestry group, Article, Athabaskan (people), clinical article, consensus, controlled study, female, genome, genotype, history, human, population, priority journal, single nucleotide polymorphism, Western Hemisphere, biological model, gene flow, genetics, migration, Russian Federation, United States, Americas, History, Ancient, Human Migration, Humans, Indians, North American, Models, Genetic, Siberia

Аннотация: How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more thПоказать полностьюan an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericues and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. © 2015, American Association for the Advancement of Science. All rights reserved.

Журнал: Science

Выпуск журнала: Vol. 349, Is. 6250

• Raghavan M. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Steinr?cken M. (Computer Science Division, University of California, Berkeley, Berkeley, CA, United States, Department of Statistics, University of California, Berkeley, Berkeley, CA, United States, Department of Biostatistics and Epidemiology, Universit)
• Harris K. (Department of Mathematics, University of California, Berkeley, Berkeley, CA, United States)
• Schiffels S. (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom)
• Rasmussen S. (Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet, Building 208, Kongens Lyngby, Denmark)
• DeGiorgio M. (Departmentof Biology and Statistics, Pennsylvania State University, 502 Wartik Laboratory, University Park, PA, United States)
• Albrechtsen A. (Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maal?es Vej 5, Copenhagen, Denmark)
• Valdiosera C. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Department of Archaeology and History, La Trobe University, Melbourne, VIC, Australia)
• Ávila-Arcos M.C. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, )
• Malaspinas A.-S. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Eriksson A. (Department of Zoology, University of Cambridge, Downing Street, Cambridge, United Kingdom, Integrative Systems Biology Laboratory, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia)
• Moltke I. (Bioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maal?es Vej 5, Copenhagen, Denmark)
• Metspalu M. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Department of Evolutionary Biology, University of Tartu, Tartu, Estonia)
• Homburger J.R. (Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA, United States)
• Wall J. (Institute for Human Genetics, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA, United States)
• Cornejo O.E. (School of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA, United States)
• Moreno-Mayar J.V. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Korneliussen T.S. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Pierre T. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Rasmussen M. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stan)
• Campos P.F. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Centro de Investigaci?n en Ciencias del Mar y Limnolog?a/Centro Interdisciplinar de Investiga??o Marinha e Ambienta)
• De Barros Damgaard P. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Allentoft M.E. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Lindo J. (Department of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL, United States)
• Metspalu E. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Department of Evolutionary Biology, University of Tartu, Tartu, Estonia)
• Rodriguez-Varela R. (Centro Mixto, Universidad Complutense de Madrid, Instituto de Salud Carlos III de Evoluci?n y Comportamiento Humano, Madrid, Spain)
• Mansilla J. (Instituto Nacional de Antropolog?a e Historia, Moneda 13, Centro, Cuauht?moc, Mexico City, Mexico)
• Henrickson C. (University of Utah, Department of Anthropology, 270 S 1400 E, Salt Lake City, UT, United States)
• Seguin-Orlando A. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Malmst?m H. (Department of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyv?gen 18D, Uppsala, Sweden)
• Stafford T. (Jr., Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Acceleration Mass Spectrometry 14C Dating Centre, Department of Physics and Astronomy, Aarhus University, Ny M)
• Shringarpure S.S. (Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA, United States)
• Moreno-Estrada A. (Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA, United States, Laboratorio Nacional de Gen?mica para la Biodiversidad (LANGEBIO), Centro de Investigaci?n y de )
• Karmin M. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Department of Evolutionary Biology, University of Tartu, Tartu, Estonia)
• Tambets K. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia)
• Bergstr?m A. (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom)
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• Warmuth V. (Genetics Institute, University College London, Gower Street, London, United Kingdom, Evolutionsbiologiskt Centrum, Norbyv?gen 18D, Uppsala, Sweden)
• Singarayer J. (Centre for Past Climate Change, Department of Meteorology, University of Reading, Earley Gate, Post Office Box 243, Reading, United Kingdom)
• Valdes P. (School of Geographical Sciences, University Road, Clifton, Bristol, United Kingdom)
• Balloux F. (Genetics Institute, University College London, Gower Street, London, United Kingdom)
• Leboreiro I. (Instituto Nacional de Antropolog?a e Historia, Moneda 13, Centro, Cuauht?moc, Mexico City, Mexico)
• Vera J.L. (Escuela Nacional de Antropolog?a e Historia, Perif?rico Sur y Zapote s/n Colonia Isidro Fabela, Tlalpan, Isidro Fabela, Mexico City, Mexico)
• Rangel-Villalobos H. (Instituto de Investigaci?n en Gen?tica Molecular, Universidad de Guadalajara, Ocotl?n, Mexico)
• Pettener D. (Dipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Universit? di Bologna, Via Selmi 3, Bologna, Italy)
• Luiselli D. (Dipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Universit? di Bologna, Via Selmi 3, Bologna, Italy)
• Davis L.G. (Department of Anthropology, Oregon State University, 238 Waldo Hall, Corvallis, OR, United States)
• Heyer E. (Museum National d'Histoire Naturelle, CNRS, Universit? Paris 7 Diderot, Paris, France)
• Zollikofer C.P.E. (Anthropological Institute and Museum, University of Z?rich, Winterthurerstrasse 190, Z?rich, Switzerland)
• Ponce De Le?n M.S. (Anthropological Institute and Museum, University of Z?rich, Winterthurerstrasse 190, Z?rich, Switzerland)
• Smith C.I. (Department of Archaeology and History, La Trobe University, Melbourne, VIC, Australia)
• Grimes V. (Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, Canada, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany)
• Pike K.-A. (Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, Canada)
• Deal M. (Department of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, Canada)
• Fuller B.T. (Department of Earth System Science, University of California, Irvine, Keck Carbon Cycle Accelerator Mass Spectrometry Group, B321 Croul Hall, Irvine, CA, United States)
• Arriaza B. (Instituto de Alta Investigaci?n, Universidad de Tarapac?, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile)
• Standen V. (Departamento de Antropologia, Universidad de Tarapac?, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile)
• Luz M.F. (Funda??o Museu do Homem Americano, Centro Cultural S?rgio Motta, Campestre, Sao Raimundo Nonato, Brazil)
• Ricaut F. (Laboratoire d'Anthropologie Mol?culaire et Imag?rie de Synth?se UMR-5288, CNRS, Universit? de Toulouse, Toulouse, France)
• Guidon N. (Funda??o Museu do Homem Americano, Centro Cultural S?rgio Motta, Campestre, Sao Raimundo Nonato, Brazil)
• Osipova L. (Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, Russian Federation, Novosibirsk State University, 2 Pirogova Street, Novosibirsk, Russian Federation)
• Voevoda M.I. (Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, Russian Federation, Institute of Internal Medicine, Siberian Branch of RAS, 175/1 ul. B. Bogatkova, Novosibirsk, R)
• Posukh O.L. (Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, Russian Federation, Novosibirsk State University, 2 Pirogova Street, Novosibirsk, Russian Federation)
• Balanovsky O. (Vavilov Institute of General Genetics, Gubkina 3, Moscow, Russian Federation, Research Centre for Medical Genetics, Moskvorechie 1, Moscow, Russian Federation)
• Lavryashina M. (Kemerovo State University, Krasnaya 3, Kemerovo, Russian Federation)
• Bogunov Y. (Vavilov Institute of General Genetics, Gubkina 3, Moscow, Russian Federation)
• Khusnutdinova E. (Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, Ufa, Russian Federation, Department of Genetics and Fundamental Medicine, Bashkir State University, Zaki Validi 32, Ufa)
• Gubina M. (Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, Russian Federation)
• Balanovska E. (Research Centre for Medical Genetics, Moskvorechie 1, Moscow, Russian Federation)
• Fedorova S. (Department of Molecular Genetics, Yakut Scientific Centre of Complex Medical Problems, Sergelyahskoe Shosse 4, Yakutsk, Russian Federation, Laboratory of Molecular Biology, Institute of Natural Sciences, M. K. Ammosov North-Eastern Federal U)
• Litvinov S. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, Ufa, Russian Federation)
• Malyarchuk B. (Institute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan, Russian Federation)
• Derenko M. (Institute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan, Russian Federation)
• Mosher M.J. (Department of Anthropology, Western Washington University, Bellingham, WA, United States)
• Archer D. (Department of Anthropology, Northwest Community College, 353 Fifth Street, 65Prince RupertBC, Canada)
• Cybulski J. (Canadian Museum of History, 100 Rue Laurier, Gatineau, QC, Canada, University of Western Ontario, London, ON, Canada, Simon Fraser University, Burnaby, BC, Canada)
• Petzelt B. (Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC, Canada)
• Mitchell J. (Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC, Canada)
• Worl R. (Sealaska Heritage Institute, 105 S. Seward Street, Juneau, AK, United States)
• Norman P.J. (Department of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA, United States)
• Parham P. (Department of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA, United States)
• Kemp B.M. (School of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA, United States, Department of Anthropology, Washington State University, Pullman, WA, United States)
• Kivisild T. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Division of Biological Anthropology, University of Cambridge, Henry Wellcome Building, Fitzwilliam Street, Cambridge, United Kingdom)
• Tyler-Smith C. (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom)
• Sandhu M.S. (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Cam)
• Crawford M. (Laboratory of Biological Anthropology, University of Kansas, 1415 Jayhawk Boulevard, 622 Fraser Hall, Lawrence, KS, United States)
• Villems R. (Estonian Biocentre, Evolutionary Biology Group, Tartu, Estonia, Department of Evolutionary Biology, University of Tartu, Tartu, Estonia)
• Smith D.G. (KSMolecular Anthropology Laboratory, Department of Anthropology, University of California, One Shields Avenue, Davis, United States)
• Waters M.R. (Center for the Study of the First Americans, Texas A and M University, College Station, United States, Department of Anthropology, Texas A and M University, College Station, TX, United States, Department of Geography, Texas A and M Universit)
• Goebel T. (Center for the Study of the First Americans, Texas A and M University, College Station, United States)
• Johnson J.R. (Santa Barbara Museum of Natural History, 2559 Puesta del Sol, Santa Barbara, CA, United States)
• Malhi R.S. (Department of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL, United States, Carle R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States)
• Jakobsson M. (Department of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyv?gen 18D, Uppsala, Sweden)
• Meltzer D.J. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark, Department of Anthropology, Southern Methodist University, Dallas, TX, United States)
• Manica A. (Department of Zoology, University of Cambridge, Downing Street, Cambridge, United Kingdom)
• Durbin R. (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom)
• Bustamante C.D. (Department of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA, United States)
• Song Y.S. (Computer Science Division, University of California, Berkeley, Berkeley, CA, United States, Department of Statistics, University of California, Berkeley, Berkeley, CA, United States, Department of Integrative Biology, University of California,)
• Nielsen R. (Department of Integrative Biology, University of California, 3060 Valley Life Sciences Building 3140, Berkeley, CA, United States)
• Willerslev E. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)
• Raghavan M. (Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, ?ster Voldgade 5-7, Copenhagen, Denmark)

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