Functional divergence between evolutionary-related LuxG and Fre oxidoreductases of luminous bacteria

Описание

Тип публикации: статья из журнала

Год издания: 2019

Идентификатор DOI: 10.1002/prot.25696

Ключевые слова: bacterial bioluminescence, Fre, functional divergence, gene duplication, LuxG, NAD(P)H:flavin-oxidoreductase

Аннотация: In luminous bacteria NAD(P)H:flavin-oxidoreductases LuxG and Fre, there are homologous enzymes that could provide a luciferase with reduced flavin. Although Fre functions as a housekeeping enzyme, LuxG appears to be a source of reduced flavin for biolumin

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Издание

Журнал: Proteins: Structure, Function and Bioinformatics

ISSN журнала: 08873585

Издатель: John Wiley and Sons Inc.

Персоны

  • Deeva Anna A. (Siberian Fed Univ, Lab Bioluminescent Biotechnol, Svobodny Prosp 79, Krasnoyarsk 660041, Russia)
  • Zykova Evgenia A. (RAS, Inst Cell Biophys, Mech Cell Genome Functioning Lab, Pushchino, Moscow Region, Russia; State Inst Informat Technol & Telecommun SIIT & T, Dept Appl Res Informatizat, Moscow, Russia)
  • Nemtseva Elena V. (Siberian Fed Univ, Lab Bioluminescent Biotechnol, Svobodny Prosp 79, Krasnoyarsk 660041, Russia; RAS, Fed Res Ctr, Krasnoyarsk Sci Ctr SB, Lab Photobiol,Inst Biophys SB, Krasnoyarsk, RussiaArticle)
  • Kratasyuk Valentina A. (Siberian Fed Univ, Lab Bioluminescent Biotechnol, Svobodny Prosp 79, Krasnoyarsk 660041, Russia; RAS, Fed Res Ctr, Krasnoyarsk Sci Ctr SB, Lab Photobiol,Inst Biophys SB, Krasnoyarsk, RussiaArticle)