Тип публикации: статья из журнала

Год издания: 2015

Идентификатор DOI: 10.1134/S1990750815020067

Ключевые слова: baclofen, poisoning, diagnostics, HPLC-MS/MS, 4 amino 3 phenylbutyric acid, Article, blood sampling, controlled study, diagnostic test accuracy study, drug blood level, drug determination, drug identification, drug intoxication, high performance liquid chromatography, human, limit of quantitation, mass spectrometry, priority journal, process development, quantitative analysis, reproducibility, sensitivity and specificity, toxicity testing

Аннотация: A method of identification and quantitative determination of baclofen in blood by HPLC with mass spectrometry detection has been developed. It is characterized by high sensitivity, specificity, linearity, accuracy, reproducibility, and a low detection for quantitative determination. The method has been used for diagnostics of acuteПоказать полностьюbaclofen poisoning in patients.

Журнал: Biochemistry Moscow-Supplement Series B-Biomedical Chemistry

Выпуск журнала: Vol. 9, Is. 2

Номера страниц: 137-142

ISSN журнала: 19907508

Место издания: MOSCOW

Издатель: MAIK NAUKA-INTERPERIODICA

• Dukova O.A. (Krasnoyarsk Regional Bureau of Forensic Medical Expertise)
• Efremov A.A. (Siberian Federal University)
• Suvorova E.V. (Krasnoyarsk Regional Bureau of Forensic Medical Expertise)
• Kotlovsky M.Y. (Central Research Laboratory, Voyno-Yasenetsky Krasnoyarsk Medical University)
• Pokrovsky A.A. (Central Research Laboratory, Voyno-Yasenetsky Krasnoyarsk Medical University)
• Shivrina T.G. (Karpovich Municipal Clinical Emergency Hospital no. 6)
• Krasnov E.A. (Siberian Medical University)

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