Тип публикации: статья из журнала

Год издания: 2024

Идентификатор DOI: 10.1039/d4ra03398a

Аннотация: Polyhydroxyalkanoates (PHAs) are used for various biomedical applications due to their biocompatibility. Surface properties, such as surface roughness, are crucial for PHAs performance. Traditional parameters used for the characterization of surface roughness, such as Ra, are often insufficient to capture the complex and hierarchicПоказать полностьюal (multiscale) topography of PHA films. We measure the topography and surface roughness of thin PHA films with atomic force microscopy and analyze the topography data using several relatively novel data processing methods, including the calculation of autocorrelation functions, topological data analysis, and the distribution of minimum and maximum values of pixels over the topography data. The results provide details of multiscale and anisotropic surface properties that are crucial to PHAs biocompatibility but often overlooked by traditional topography analysis methods.

Журнал: RSC Advances

Выпуск журнала: Т. 14, № 27

Номера страниц: 19603-19611

ISSN журнала: 20462069

• Ghorabe Fares D. E. (Infochemistry Scientific Center, ITMO University, Lomonosova St. 9, 191002 St. Petersburg, Russia)
• Aglikov Aleksandr (Infochemistry Scientific Center, ITMO University, Lomonosova St. 9, 191002 St. Petersburg, Russia)
• Novikov Alexander S. (Infochemistry Scientific Center, ITMO University, Lomonosova St. 9, 191002 St. Petersburg, Russia)
• Nosonovsky Michael (Mechanical Engineering, University of Wisconsin-Milwaukee, 3200 N Cramer St., Milwaukee, WI 53211, USA)
• Ryltseva Galina A. (School of Fundamental Biology and Biotechnology, Siberian Federal University, Svobodnyi Av. 79, 660041 Krasnoyarsk, Russia)
• Dudaev Alexey E. (Institute of Biophysics SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, Akademgorodok, 50/50, 660036 Krasnoyarsk, Russia)
• Menzianova Natalia G. (School of Fundamental Biology and Biotechnology, Siberian Federal University, Svobodnyi Av. 79, 660041 Krasnoyarsk, Russia)
• Skorb Ekaterina V. (Infochemistry Scientific Center, ITMO University, Lomonosova St. 9, 191002 St. Petersburg, Russia)
• Shishatskaya Ekaterina I. (Infochemistry Scientific Center, ITMO University, Lomonosova St. 9, 191002 St. Petersburg, Russia)

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