Optimizing Neural Networks for Chemical Reaction Prediction: Insights from Methylene Blue Reduction Reactions

Описание

Тип публикации: статья из журнала

Год издания: 2024

Идентификатор DOI: 10.3390/ijms25073860

Аннотация: <jats:p>This paper offers a thorough investigation of hyperparameter tuning for neural network architectures using datasets encompassing various combinations of Methylene Blue (MB) Reduction by Ascorbic Acid (AA) reactions with different solvents and concentrations. The aim is to predict coefficients of decay plots for MB absorbancПоказать полностьюe, shedding light on the complex dynamics of chemical reactions. Our findings reveal that the optimal model, determined through our investigation, consists of five hidden layers, each with sixteen neurons and employing the Swish activation function. This model yields an NMSE of 0.05, 0.03, and 0.04 for predicting the coefficients A, B, and C, respectively, in the exponential decay equation A + B · e−x/C. These findings contribute to the realm of drug design based on machine learning, providing valuable insights into optimizing chemical reaction predictions.</jats:p>

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Издание

Журнал: International Journal of Molecular Sciences

Выпуск журнала: Т. 25, 7

Номера страниц: 3860

ISSN журнала: 16616596

Место издания: Basel

Издатель: Molecular Diversity Preservation International

Персоны

  • Malashin Ivan (Artificial Intelligence Technology Scientific and Education Center, Bauman Moscow State Technical University, 105005 Moscow, Russia)
  • Tynchenko Vadim (Artificial Intelligence Technology Scientific and Education Center, Bauman Moscow State Technical University, 105005 Moscow, Russia)
  • Gantimurov Andrei (Artificial Intelligence Technology Scientific and Education Center, Bauman Moscow State Technical University, 105005 Moscow, Russia)
  • Nelyub Vladimir (Artificial Intelligence Technology Scientific and Education Center, Bauman Moscow State Technical University, 105005 Moscow, Russia)
  • Borodulin Aleksei (Artificial Intelligence Technology Scientific and Education Center, Bauman Moscow State Technical University, 105005 Moscow, Russia)

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