Тип публикации: статья из журнала

Год издания: 2017

Идентификатор DOI: 10.1134/S1607672917050076

Ключевые слова: calcium phosphate, 10103-46-5, 13767-12-9, 14358-97-5, 7758-87-4, osteocalcin, 136461-80-8, calcium phosphate, Calcium Phosphates, Osteocalcin

Аннотация: The Cell-IQ continuous surveillance system allowed us to establish the following changes in a 14- day culture in vitro: a twofold suppression of the directional migration of multipotent mesenchymal stromal cells of human adipose tissue (MMSC-AT) towards the samples with a microarc calcium phosphate (CP) coating from synthetic hydroПоказать полностьюxyapatite; a tenfold decrease in the cell mass on the interphase with the samples, which was accompanied by a slight reduction in the expression of membrane determinants of stromal stem cells; and an enhancement of their osteogenic differentiation (osteocalcin secretion and mineralized matrix formation) on the 21st day of the study. Calcium phosphate particles, but not the calcium and phosphorus ions, may trigger the phenotypic transformation of the MMSC-AT behavior in vitro. © 2017, Pleiades Publishing, Ltd.

Журнал: Doklady Biochemistry and Biophysics

Выпуск журнала: Vol. 476, Is. 1

Номера страниц: 310-315

ISSN журнала: 16076729

Издатель: Maik Nauka Publishing / Springer SBM

• Litvinova L.S. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Shupletsova V.V. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Yurova K.A. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Khaziakhmatova O.G. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Todosenko N.M. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Khlusova M.Y. (Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russian Federation)
• Slepchenko G.B. (Tomsk Polytechnic University, Tomsk, Russian Federation)
• Cherempey E.G. (Tomsk Polytechnic University, Tomsk, Russian Federation)
• Sharkeev Y.P. (Tomsk Polytechnic University, Tomsk, Russian Federation, Institute of Strength Physics and Materials Science, Siberian Branch, Russian Academy of Sciences, Tomsk, Russian Federation)
• Komarova E.G. (Institute of Strength Physics and Materials Science, Siberian Branch, Russian Academy of Sciences, Tomsk, Russian Federation)
• Sedelnikova M.B. (Institute of Strength Physics and Materials Science, Siberian Branch, Russian Academy of Sciences, Tomsk, Russian Federation)
• Malashchenko V.V. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Melashchenko E.S. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation)
• Khlusov I.A. (Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russian Federation, Tomsk Polytechnic University, Tomsk, Russian Federation)

• Scopus