Assessment of Biomedical Risk Factors Associated with Adverse Pregnancy Outcomes : научное издание

Описание

Тип публикации: статья из журнала

Год издания: 2020

Идентификатор DOI: 10.1007/978-3-030-63322-6_75

Ключевые слова: binary data, biomedical risk factors, odds ratio

Аннотация: Purpose of research is determine the risk factors for premature birth using the data of perinatal monitoring of the Krasnoyarsk territory. Methods: retrospective case-control study of 118412 pregnant women. The analyzed data set is described by a binary context - a matrix, the rows of which correspond to units of observation as a cПоказать полностьюase of pregnancy with a favorable and an adverse outcome, and the columns - to the biomedical risk factors for each cases. Researched by 54 risk factors on obstetric and gynecological medical history and somatic diseases of the mother. The multi-calculater of odds ratio has been developed which can calculating an odds ratios simultaneously for all risk factors from dataset, with the help of which the influence of biomedical factors on the risk of premature birth is analyzed. The calculations are implemented by a programming language R. According to the studied statistical material, 31 factors were established that increase the chances of detecting a risk factor in the group “Preterm birth”, the revealed relationship of factors with outcome is statistically significant at p< 0.05. To the greatest extent, this risk is influenced by the presence of a positive reaction to lupus anticoagulant, diabetes mellitus, hypertension of II and III severity in the mother.

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Издание

Журнал: Advances in Intelligent Systems and Computing (см. в книгах)

Выпуск журнала: Т. 1294

Номера страниц: 883-893

ISSN журнала: 21945357

Персоны

  • Lukyanova N. (Institute of Mathematics and Computer Science of Siberian Federal University)
  • Melnikova O. (Reshetnev Siberian State University of Science and Technology)

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