Тип публикации: статья из журнала
Год издания: 2015
Идентификатор DOI: 10.1080/09205063.2015.1082810
Ключевые слова: laser processing, biopolymers, polymer materials, poly(3-hydroxybutyrate), biocompatibility, Biomechanics, Bone, Cell culture, Pulsed lasers, Scaffolds (biology), Stem cells, 3t3 mouse fibroblasts, Bone marrow, Bone regeneration, Laser process, Mesenchymal stem cell, Poly-3-hydroxybutyrate, Pulsed mode, Laser materials processing, poly(3 hydroxybutyric acid), artificial membrane, hydroxybutyric acid, poly-beta-hydroxybutyrate, polyester, polymer, 3T3 cell line, animal cell, Article, bone marrow derived mesenchymal stem cell, carbon dioxide laser, cell adhesion, controlled study, fibroblast, mouse, multipotent stem cell, nonhuman, priority journal, animal, bone marrow cell, cell survival, chemistry, comparative study, Cupriavidus necator, cytology, gas laser, human, mesenchymal stroma cell, metabolism, porosity, radiation response, surface property, tensile strength, tissue scaffold, ultrastructure, Wistar rat, Young modulus, Animals, Bone Marrow Cells, Cells, Cultured, Elastic Modulus, Humans, Hydroxybutyrates, Lasers, Gas, Membranes, Artificial, Mesenchymal Stromal Cells, Mice, NIH 3T3 Cells, Polyesters, Polymers, Rats, Wistar, Surface Properties, Tissue Scaffolds
Аннотация: CO2 laser radiation was used to process poly(3-hydroxybutyrate) constructs - films and 3D pressed plates. Laser processing increased the biocompatibility of unperforated films treated with moderate uniform radiation, as estimated by the number and degree of adhesion of NIH 3T3 mouse fibroblast cells. The biocompatibility of perforaПоказать полностьюted films modified in the pulsed mode did not change significantly. At the same time, pulsed laser processing of the 3D plates produced perforated scaffolds with improved mechanical properties and high biocompatibility with bone marrow-derived multipotent, mesenchymal stem cells, which show great promise for bone regeneration.
Журнал: JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
Выпуск журнала: Vol. 26, Is. 16
Номера страниц: 1210-1228
ISSN журнала: 09205063
Место издания: ABINGDON
Издатель: TAYLOR & FRANCIS LTD