Тип публикации: доклад, тезисы доклада, статья из сборника материалов конференций
Год издания: 2020
Идентификатор DOI: 10.18699/BGRS/SB-2020-160
Ключевые слова: adolescents, internet addiction, gene polymorphism
Аннотация: The rapid emergence and spread of Internet addiction in adolescent populations, combined with a rapid change in consumed content due to mobile access availability and the new access devices, are new challenges for classical psychology and fundamental medicine that require urgent solutions. The presence of the genetic component of IПоказать полностьюnternet addiction was convincingly shown in different populations, but to date the specific genes involved in the mechanisms of such heritability have not been well identified. The aim of the study was to investigate the role of candidate neurotransmitters and to perform a population analysis of candidate genes polymorphisms for the Internet addiction formation. As a result of the analysis, 7 Internet-dependent adolescents and 39 adolescents with a tendency to Internet-dependent behavior were identified. The frequencies of genotype distribution in the population sampling of Caucasians (n = 302) were obtained: * CC 59.6%, * CT 40.4%, * TT 0% (rs1800497 DRD2); * AA 23.8%, AG 52.4%, * GG 23.8% (rs4680 COMT); * CC 37.4%, * CG 46.0%, * GG 16.6% (rs2229910 NTRK3). The results will help to open new perspectives in assessing the fundamental neurobiological causes for the Internet addiction and the personalization of therapeutic approaches in Internet dependent adolescents.
Журнал: BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE/SYSTEMS BIOLOGY (BGRS/SB-2020)
Номера страниц: 253-254
Издатель: Institute of Cytology and Genetics, SB RAS