Перевод названия: GC-MS determination of non-volatile components of diluents in plastic smoking blends containing synthetic cannabinoids
Тип публикации: статья из журнала
Год издания: 2019
Идентификатор DOI: 10.29296/25877313-2019-04-04
Ключевые слова: курительные смеси, синтетические каннабиноиды, наполнитель, нелетучие органические соединения, ГХ-МС определение, smoking blends, Synthetic cannabinoids, cutting agent, non-volatile organic components, GC-MS determination
Аннотация: Для идентификации нелетучих компонентов наполнителей в пластичных курительных смесях, содержащих синтетические каннабиноиды, использован метод хромато-масс-спектрометрии (ГХ-МС) с предварительной дериватизацией образцов. Впервые установлены основные нелетучие компоненты наполнителей: глицерин, моносахариды, дисахариды, сорбитол и оПоказать полностьюксикислоты. Over the last decade a spread of novel psychoactive substances including synthetic cannabinoids (SC) has become a serious social problem. SC cause addiction and present a danger to life and health of people. Cutting agents are substances used to dilute drugs, psychotropic and potent substances in illicit trafficking. Determination of the qualitative and quantitative composition of the cutting agents has a high forensic significance as for assessing the potential risk to the health of consumers, as for establishing the generality of the source of manufacture of samples containing narcotic drugs. The aim of this study is the GC-MS determination of non-volatile organic components of cutting agents in SC-containing plastic smoking mixtures with the preparation of appropriate derivatives of non-volatile organic components. SC-containing plastic smoking mixtures, had withdrawn from the illegal circulation of the Transport Administration of the Ministry of Internal Affairs of Russia in the Siberian Federal District in the period from 2016 to 2018, were used. 15 samples were analyzed. Sample preparation. The dry residue of water-soluble substances was treated with derivatizing reagents: 0.2 ml of pyridine solution containing hydroxylamine hydrochloride at a concentration of 25 mg/ml was added to the dry residue. Then solution was kept at a temperature of 70 °C until the precipitate dissolved. Then, 10
Журнал: Вопросы биологической, медицинской и фармацевтической химии
Выпуск журнала: Т. 22, № 4
Номера страниц: 24-28
ISSN журнала: 15609596
Место издания: Москва
Издатель: Общество с ограниченной ответственностью Издательский дом Русский врач