Тип публикации: статья из журнала
Год издания: 2015
Ключевые слова: Intravesical administration, Pharmacokinetics, Prospidine, prospidium chloride, animal experiment, Article, drug blood level, nonhuman, radioactivity, rat, systemic circulation
Аннотация: The pharmacokinetics of anticancer drug prospidine in intact rats has been studied upon intravesical administration at a dose of 100 mg/kg. It is established that the maximum concentration of the drug with specific radioactivity 10 ?curie 14C per 10 mg in the systemic circulation is achieved in 10 min after introduction and amountsПоказать полностьюto 140 ?g/mL. After 2 h, prospidine was present in the plasma in trace amounts. © 2015, Izdatel'stvo Meditsina. All rights reserved.
Журнал: Eksperimental'naya i Klinicheskaya Farmakologiya
Выпуск журнала: Vol. 78, Is. 4
Номера страниц: 22-24