Numerical Optimization of the Galactomannan Sulfation Process with a Sulfamic Acid-Urea Complex

Описание

Тип публикации: доклад, тезисы доклада, статья из сборника материалов конференций

Конференция: Springer Science and Business Media Deutschland GmbH; 14 October 2020 through 17 October 2020; 14 October 2020 through 17 October 2020

Год издания: 2020

Идентификатор DOI: 10.1007/978-3-030-63319-6_52

Ключевые слова: galactomannan, optimization, sulfamic acid, sulfation, urea

Аннотация: The process of sulfation of galactomannan of herbaceous plants with complex of sulfamic acid and urea, was optimized. The influence of varying factors was established - the ratio of sulfamic acid: urea (SAA: U), the ratio of galactomannan: sulfating complex (GM: SC) and the duration of the process on the degree of substitution in tПоказать полностьюhe obtained galactomannan sulfate. The data of analysis of variance for the obtained mathematical models indicate good prognostic properties. The optimal conditions for galactomannan sulfation, which provide water-soluble sulfated galactomannan with a high (0.89) degree of substitution, have been established. The optimal conditions for the process of sulfation of galactomannan of herbaceous plants amount of urea (mol) per 1 mol of SAA – 2.26 mol, amount of SC (mol) per 1 mol of GM – 3.9 mol and process time – 118 min. Sulfated galactomannan of herbaceous plants can be used as a substitute for animal-derived anticoagulant heparin. © 2020, The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.

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Издание

Журнал: Advances in Intelligent Systems and Computing

Выпуск журнала: Vol. 1295

Номера страниц: 567-574

ISSN журнала: 00253159

Персоны

  • Kazachenko A.S. (Institute of Chemistry and Chemical Technology SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, Akademgorodok, 50/24, Krasnoyarsk, 660036, Russian Federation, Siberian Federal University, Svobodny Av., 79, Krasnoyarsk, 660041, Russian Federation)
  • Vasilyeva N.Y. (Institute of Chemistry and Chemical Technology SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, Akademgorodok, 50/24, Krasnoyarsk, 660036, Russian Federation, Siberian Federal University, Svobodny Av., 79, Krasnoyarsk, 660041, Russian Federation)
  • Malyar Y.N. (Institute of Chemistry and Chemical Technology SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, Akademgorodok, 50/24, Krasnoyarsk, 660036, Russian Federation, Siberian Federal University, Svobodny Av., 79, Krasnoyarsk, 660041, Russian Federation)

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