Тип публикации: статья из журнала
Год издания: 2021
Идентификатор DOI: 10.3390/molecules26175364
Ключевые слова: arabinogalactan, larix sibirica ledeb, sulfated arabinogalactan, molecular weight distribution, gel permeation chromatography, optimization, sulfation
Аннотация: The process of sulfation of arabinogalactan-a natural polysaccharide from Larix sibirica Ledeb.-with sulfamic acid in 1,4-dioxane using different activators has been studied for the first time. The dynamics of the molecular weight of sulfated arabinogalactan upon variation in the temperature and time of sulfation of arabinogalactanПоказать полностьюwith sulfamic acid in 1,4-dioxane has been investigated. It has been found that, as the sulfation time increases from 10 to 90 min, the molecular weights of the reaction products grow due to the introduction of sulfate groups without significant destruction of the initial polymer and sulfation products. Sulfation at 95 degrees C for 20 min yields the products with a higher molecular weight than in the case of sulfation at 85 degrees C, which is related to an increase in the sulfation rate; however, during the further process occurring under these conditions, sulfation is accompanied by the destruction and the molecular weight of the sulfated polymer decreases. The numerical optimization of arabinogalactan sulfation process has been performed. It has been shown that the optimal parameters for obtaining a product with a high sulfur content are a sulfamic acid amount of 20 mmol per 1 g of arabinogalactan, a process temperature of 85 degrees C, and a process time of 2.5 h.
Журнал: MOLECULES
Выпуск журнала: Vol. 26, Is. 17
Номера страниц: 5364
ISSN журнала: 14203049
Место издания: BASEL
Издатель: MDPI