DNA methylation changes in clonally propagated oil palm : научное издание

Описание

Тип публикации: статья из журнала

Год издания: 2020

Идентификатор DOI: 10.1007/s00299-020-02561-9

Ключевые слова: mantling, epigenetics, whole-genome bisulfite sequencing, karma

Аннотация: Key message Several hypomethylated sites within theKarmaregion of EgDEF1and hotspot regions in chromosomes 1, 2, 3, and 5 may be associated with mantling. One of the main challenges faced by the oil palm industry is fruit abnormalities, such as the "mantled" phenotype that can lead to reduced yields. This clonal abnormality is an eПоказать полностьюpigenetic phenomenon and has been linked to the hypomethylation of a transposable element within the EgDEF1gene. To understand the epigenome changes in clones, methylomes of clonal oil palms were compared to methylomes of seedling-derived oil palms. Whole-genome bisulfite sequencing data from seedlings, normal, and mantled clones were analyzed to determine and compare the context-specific DNA methylomes. In seedlings, coding and regulatory regions are generally hypomethylated while introns and repeats are extensively methylated. Genes with a low number of guanines and cytosines in the third position of codons (GC(3)-poor genes) were increasingly methylated towards their 3 ' region, while GC(3)-rich genes remain demethylated, similar to patterns in other eukaryotic species. Predicted promoter regions were generally hypomethylated in seedlings. In clones, CG, CHG, and CHH methylation levels generally decreased in functionally important regions, such as promoters, 5 ' UTRs, and coding regions. Although random regions were found to be hypomethylated in clonal genomes, hypomethylation of certain hotspot regions may be associated with the clonal mantling phenotype. Our findings, therefore, suggest other hypomethylated CHG sites within theKarmaof EgDEF1and hypomethylated hotspot regions in chromosomes 1, 2, 3 and 5, are associated with mantling.

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Издание

Журнал: PLANT CELL REPORTS

Выпуск журнала: Vol. 39, Is. 9

Номера страниц: 1219-1233

ISSN журнала: 07217714

Место издания: NEW YORK

Издатель: SPRINGER

Персоны

  • Sarpan Norashikin (Malaysian Palm Oil Board, Adv Biotechnol & Breeding Ctr, 6 Persiaran Inst, Kajang 43000, Selangor, Malaysia)
  • Taranenko Elizaveta (Univ La Verne, Dept Biol, La Verne, CA 91750 USA; Siberian Fed Univ, Dept Fundamental Biol & Biotechnol, Krasnoyarsk 660074, Russia)
  • Ooi Siew-Eng (Malaysian Palm Oil Board, Adv Biotechnol & Breeding Ctr, 6 Persiaran Inst, Kajang 43000, Selangor, Malaysia)
  • Low Eng-Ti Leslie (Malaysian Palm Oil Board, Adv Biotechnol & Breeding Ctr, 6 Persiaran Inst, Kajang 43000, Selangor, Malaysia)
  • Espinoza Alejandro (Univ La Verne, Dept Biol, La Verne, CA 91750 USA)
  • Tatarinova Tatiana V. (Univ La Verne, Dept Biol, La Verne, CA 91750 USA; Siberian Fed Univ, Dept Fundamental Biol & Biotechnol, Krasnoyarsk 660074, Russia; Vavilov Inst Gen Genet, Moscow, Russia; Russian Acad Sci, AA Kharkevich Inst Informat Transmiss Problems, Moscow, Russia)
  • Ong-Abdullah Meilina (Malaysian Palm Oil Board, Adv Biotechnol & Breeding Ctr, 6 Persiaran Inst, Kajang 43000, Selangor, Malaysia)

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