Тип публикации: статья из журнала
Год издания: 2009
Ключевые слова: fluoroquinolone, ciprofloxacin, sulfuric acid, crystal structure, hydrogen bonds
Аннотация: A new compound of C17H20FN3O32+center dot 2HSO(4)(-)center dot H2O [ciprofloxacindi-um bis(hydrosulfate) monohydrate], C17H18FN3O3 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (CfH, ciprofloxacin) is obtained and its crystal structure is determined. The crystal contains CfH32+ and HSO4- ionsПоказать полностьюand crystallization water molecules. Hydrogen (H3), which forms an intramolecular hydrogen bond with oxygen O2 of the carboxyl group, is attached to the carbonyl O1 atom. Hydrogen H4 of the carboxyl group is hydrogen bonded to the crystallization water molecule which links CfH32+ with two HSO4- groups by hydrogen bonds. Both H atoms at N3 of the piperazine ring form hydrogen bonds with two oxygen atoms of other HSO4- anions. Intramolecular hydrogen bonds of two types are present in the CfH32+ cation. One of them forms a six-membered ring, bonding O1 and O2 atoms, while the other, also enclosing a six-membered ring, links fluorine and carbon C14 atoms.
Журнал: JOURNAL OF STRUCTURAL CHEMISTRY
Выпуск журнала: Vol. 50, Is. 1
Номера страниц: 158-161
ISSN журнала: 00224766
Место издания: NEW YORK
Издатель: SPRINGER