Тип публикации: статья из журнала
Год издания: 2013
Идентификатор DOI: 10.1007/s10517-013-2053-0
Ключевые слова: resorbable polymers, Bioplastotane, controlled drug delivery systems, microparticles, Ehrlich's carcinoma, doxorubicin, drug carrier, antineoplastic antibiotic, biomaterial, hydroxybutyric acid, microcapsule, poly-beta-hydroxybutyrate, polyester, animal experiment, animal model, animal tissue, antineoplastic activity, article, cancer inhibition, controlled study, drug delivery device, drug delivery system, drug dosage form comparison, drug efficacy, drug mechanism, Ehrlich ascites tumor, encapsulation, leukocyte count, mouse, multiple cycle treatment, nonhuman, oncological parameters, tumor volume, tumor weight, animal, Bagg albino mouse, cancer transplantation, Carcinoma, Ehrlich Tumor, chemistry, drug screening, heart muscle, pathology, toxicity, Animalia, Mus, Animals, Antibiotics, Antineoplastic, Biocompatible Materials, Capsules, Drug Carriers, Drug Screening Assays, Antitumor, Hydroxybutyrates, Mice, Mice, Inbred BALB C, Myocardium, Neoplasm Transplantation, Polyesters
Аннотация: Antitumor efficiency of an experimental form of an experimental form of anthracyclin antibiotic (doxorubicin), resorbable microparticles from Bioplastotane(TM), was studied on laboratory mice with transplanted Ehrlich's solid carcinoma. Use of the experimental form of the cytostatic in polymeric microparticles from resorbable BioplПоказать полностьюastotane(TM) in animals with solid tumor led to inhibition of the cancerous process, comparable to that in response to intravenous free doxorubicin, but without negative effects on the blood system.
Журнал: BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Выпуск журнала: Vol. 154, Is. 6
Номера страниц: 773-777
ISSN журнала: 00074888
Место издания: NEW YORK
Издатель: SPRINGER