Тип публикации: статья из журнала
Год издания: 2008
Идентификатор DOI: 10.1007/s10517-009-0406-5
Ключевые слова: BCG granulomatosis, Genotype, Intrauterine hypoxia, Liver, Postnatal period, BCG vaccine, animal experiment, animal model, article, C57BL 6 mouse, CBA mouse, cell composition, cell migration, controlled study, epithelioid cell, fetus hypoxia, granulomatosis, histopathology, infection control, liver granuloma, macrophage, male, mouse, Mycobacterium tuberculosis, nonhuman, perinatal period, phagocyte, Animals, Female, Fetal Hypoxia, Granuloma, Mice, Mice, Inbred C57BL, Mice, Inbred CBA, Animalia, Mus
Аннотация: Specific features of the formation and spontaneous regression of BCG granulomas, depending on mouse genotype and history of intrauterine hypoxia, were detected in 2-month-old male CBA and C57Bl/6 mice. The numerical density of granulomas, their size and (partially) cell composition varied. There are good grounds to assume that the Показать полностьюnumber of BCG granulomas in the liver, irrespective of the experimental conditions and animal strains, decreases after elimination of M. tuberculosis persisting in granuloma phagocytes and subsequent migration of cells constituting the granuloma. © 2008 Springer Science+Business Media, Inc.
Журнал: Bulletin of Experimental Biology and Medicine
Выпуск журнала: Vol. 146, Is. 6
Номера страниц: 842-844