Тип публикации: статья из журнала
Год издания: 2014
Идентификатор DOI: 10.1016/j.tetlet.2013.11.061
Ключевые слова: Bioluminescence, Fridericia heliota, Luciferin, Modified peptide, AsLn2 tripeptide, n (omega)acylated lysine, tripeptide, tyrosine, unclassified drug, asln2 peptide, lysine derivative, n(omega) acylated lysine, peptides and proteins, protein compX, article, biosynthesis, chemical structure, chromatography, controlled study, earthworm, heteronuclear multiple bond correlation, heteronuclear single quantum coherence, mass spectrometry, nonhuman, nuclear magnetic resonance spectroscopy, protein modification, proton nuclear magnetic resonance, ultraviolet radiation, protein isolation, protein structure, Enchytraeidae
Аннотация: AsLn2, an unusual modified peptide, was isolated from the bioluminescent earthworm Fridericia heliota (Enchytraeidae). Its structure, elucidated by NMR and mass spectrometry, includes residues of tyrosine, CompX (a novel tyrosine modification product, reported in the accompanying paper), and N(omega)-acylated lysine. ChromatographyПоказать полностью, UV, and H-1 NMR data imply a close structural similarity of AsLn2 with F. heliota luciferin. AsLn2 appears to be an intermediate or by-product in F. heliota luciferin biosynthesis. (C) 2013 Elsevier Ltd. All rights reserved.
Журнал: TETRAHEDRON LETTERS
Выпуск журнала: Vol. 55, Is. 2
Номера страниц: 463-465
ISSN журнала: 00404039
Место издания: OXFORD
Издатель: PERGAMON-ELSEVIER SCIENCE LTD