The Spatial Metabolic Heterogeneity of Solid Type of Enrlich Carcinoma : научное издание

Описание

Тип публикации: статья из журнала

Год издания: 2019

Аннотация: Abstract: In this work, we investigated the NAD(P)-dependent dehydrogenase activity in different fields of the solid form of Ehrlich carcinoma. It was shown that there is a metabolic distinction between different fields of the solid tumor. In this way, there is a significant difference between the ascites and solid type of Ehrlich Показать полностьюcarcinoma. In the central area of the tested sample of tumor tissue, there is a high intensity of energetic metabolism and biosynthetic processes as opposed to the peripheral areas. Previously, we proposed the concept of nonspecific metabolic reaction of the cell in organism upon the influence of negative factors. In accordance with this concept, our results indicate the development of adaptation in the tumor cells in the central area of the tested sample.

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Издание

Журнал: Doklady Biochemistry and Biophysics

Выпуск журнала: Т. 486, 1

Номера страниц: 234-237

ISSN журнала: 16076729

Место издания: Москва

Издатель: Pleiades Publishing, Ltd. (Плеадес Паблишинг, Лтд)

Авторы

  • Inzhevatkin E.V. (International Scientific Center for Organism Extreme Conditions Research,Federal Research Center “Krasnoyarsk Science Center,” Siberian Branch,Russian Academy of Sciences)
  • Savchenko A.A. (Institute of Medical Problems of the North,Federal Research Center “Krasnoyarsk Science Center,” Siberian Branch,Russian Academy of Sciences)

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