Extraction of betulin from birch bark and study of its physico-chemical and pharmacological properties

Описание

Тип публикации: статья из журнала

Год издания: 2014

Идентификатор DOI: 10.1134/S1068162014070073

Ключевые слова: birch bark, betulin, sodium hydroxide, potassium hydroxide, gastroprotective, hepatoprotective, capillary-strengthening properties

Аннотация: Betulin-containing products were obtained in a yield of about 40% from absolutely dry birch bark. The content of betulin in the products was 74-75% or 85-89% depending on the presence of sodium or potassium hydroxide, respectively. The one-step method of extraction of high-purity betulin (97.7%) is presented. Betulin was identifiedПоказать полностьюby physic-chemical methods, i.e., elemental analysis, IR and NMR spectroscopy, and electron scanning microscopy. The thermal characteristics of betulin were also studied. It was shown that betulin exhibits gastroprotective, hepatoprotective, and capillary-strengthening properties.

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Издание

Журнал: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Выпуск журнала: Vol. 40, Is. 7

Номера страниц: 742-747

ISSN журнала: 10681620

Место издания: NEW YORK

Издатель: MAIK NAUKA/INTERPERIODICA/SPRINGER

Авторы

  • Kuznetsova S.A. (Siberian Federal University)
  • Skvortsova G.P. (Institute of Chemistry and Chemical Technology, Russian Academy of Sciences)
  • Maliar I.N. (Institute of Chemistry and Chemical Technology, Russian Academy of Sciences)
  • Skurydina E.S. (Institute of Chemistry and Chemical Technology, Russian Academy of Sciences)
  • Veselova O.F. (Krasnoyarsk State Medical University)

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